Structure of PDB 3f2o Chain B

Receptor sequence
>3f2oB (length=204) Species: 9606 (Homo sapiens) [Search protein sequence]
DYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHP
VAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGY
TTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLV
ALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNG
LDPE
3D structure
PDB3f2o Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Y31 F164 E169 T170 F171 I172 Q195 Y2 F135 E140 T141 F142 I143 Q166
BS02 peptide B S62 L63 N64 R77 P79 V80 A81 G110 T111 H125 Y129 V216 W217 G218 S33 L34 N35 R48 P50 V51 A52 G81 T82 H96 Y100 V187 W188 G189
External links
PDB RCSB:3f2o, PDBe:3f2o, PDBj:3f2o
PDBsum3f2o
PubMed20561531
UniProtQ96BD6|SPSB1_HUMAN SPRY domain-containing SOCS box protein 1 (Gene Name=SPSB1)

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