Structure of PDB 3ew5 Chain B

Receptor sequence
>3ew5B (length=166) Species: 33734 (Feline infectious peritonitis virus (strain 79-1146)) [Search protein sequence]
ILPFYKAGKVSFYQGDLDVLINFLEPDVLVNAANGDLRHVGGVARAIDVF
TGGKLTKRSKEYLKSSKAIAPGNAVLFENVLEHLSVLNAVGPRNGDSRVE
GKLCNVYKAIAKCDGKILTPLISVGIFKVKLEVSLQCLLKTVTDRDLNVF
VYTDQERVTIENFFNG
3D structure
PDB3ew5 Structure of the X (ADRP) domain of nsp3 from feline coronavirus
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1GP B A67 G76 S158 G160 F162 A32 G41 S123 G125 F127
External links
PDB RCSB:3ew5, PDBe:3ew5, PDBj:3ew5
PDBsum3ew5
PubMed19966415
UniProtQ98VG9|R1AB_FIPV Replicase polyprotein 1ab (Gene Name=rep)

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