Structure of PDB 3eg1 Chain B
Receptor sequence
>3eg1B (length=56) Species:
9606
(Homo sapiens) [
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NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPS
QYITPV
3D structure
PDB
3eg1
Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
Chain
B
Resolution
1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
Y70 D77 E98 W99 W110 P112 Y115
Y7 D14 E35 W36 W47 P49 Y52
External links
PDB
RCSB:3eg1
,
PDBe:3eg1
,
PDBj:3eg1
PDBsum
3eg1
PubMed
19906645
UniProt
P00519
|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)
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