Structure of PDB 3eg1 Chain B

Receptor sequence
>3eg1B (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPS
QYITPV
3D structure
PDB3eg1 Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Y70 D77 E98 W99 W110 P112 Y115 Y7 D14 E35 W36 W47 P49 Y52
External links
PDB RCSB:3eg1, PDBe:3eg1, PDBj:3eg1
PDBsum3eg1
PubMed19906645
UniProtP00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)

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