Structure of PDB 3ebc Chain B

Receptor sequence
>3ebcB (length=244) Species: 727 (Haemophilus influenzae) [Search protein sequence]
SFIKPIYQDINSILIGQKVKAGEPFEKLVYKFLKENLSDLTFKQYEYLND
LFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDT
ADILLVKDQFYELLDVKTRNISAQAPAIISAYKLAQTCAKMIDNKEFDLF
DINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRD
LDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
3D structure
PDB3ebc Early Interrogation and Recognition of DNA Sequence by Indirect Readout
ChainB
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Q109 N110 D111 Q138 I143 S144 Y146 K147 A205 M206 Q207 Q97 N98 D99 Q124 I129 S130 Y132 K133 A191 M192 Q193
BS02 dna B R91 G92 K93 K108 N110 S136 Y199 N201 R241 K248 R79 G80 K81 K96 N98 S122 Y185 N187 R227 K234
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3ebc, PDBe:3ebc, PDBj:3ebc
PDBsum3ebc
PubMed19081059
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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