Structure of PDB 3e73 Chain B

Receptor sequence
>3e73B (length=399) Species: 9606 (Homo sapiens) [Search protein sequence]
MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERG
LKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLT
KRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKIDPHAPNE
MLYGRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFT
AKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDY
VCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC
DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACK
FAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
3D structure
PDB3e73 Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C276 H323 C276 H323
BS02 GSH B R4 H274 C276 K317 H323 R364 P366 D367 E374 R4 H274 C276 K317 H323 R364 P366 D367 E374
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0004930 G protein-coupled receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016740 transferase activity
GO:0017124 SH3 domain binding
GO:0043295 glutathione binding
GO:0046872 metal ion binding
GO:0050750 low-density lipoprotein particle receptor binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0031179 peptide modification
GO:1990748 cellular detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e73, PDBe:3e73, PDBj:3e73
PDBsum3e73
PubMed19528316
UniProtO43813|LANC1_HUMAN Glutathione S-transferase LANCL1 (Gene Name=LANCL1)

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