Structure of PDB 3e6y Chain B

Receptor sequence
>3e6yB (length=232) Species: 4097 (Nicotiana tabacum) [Search protein sequence]
APTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSV
AYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKIC
DGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAES
TLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQ
AFDEAIAEEESYKDSTLIMQLLRDNLTLWTSD
3D structure
PDB3e6y A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B R63 R67 K129 R136 L181 N182 V185 E189 I226 N233 R60 R64 K126 R133 L178 N179 V182 E186 I218 N225
BS02 CW1 B N49 F126 K129 D222 N46 F123 K126 D214 MOAD: Kd=2.5uM
Gene Ontology
Biological Process
GO:0007165 signal transduction
GO:0008104 protein localization
Cellular Component
GO:0005737 cytoplasm

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3e6y, PDBe:3e6y, PDBj:3e6y
PDBsum3e6y
PubMed19244612
UniProtP93343|1433C_TOBAC 14-3-3-like protein C

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