Structure of PDB 3e43 Chain B

Receptor sequence
>3e43B (length=240) Species: 727 (Haemophilus influenzae) [Search protein sequence]
SFIKPIYQDINSILIGQKPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKN
PAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILL
VKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDIN
YLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQ
GFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
3D structure
PDB3e43 DNA distortion and specificity in a sequence-specific endonuclease.
ChainB
Resolution2.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Q109 N110 K129 T130 F138 N141 S144 K147 A205 Q92 N93 K112 T113 F121 N124 S127 K130 A188
BS02 dna B K93 F138 Y199 N201 A203 A204 R241 K76 F121 Y182 N184 A186 A187 R224
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e43, PDBe:3e43, PDBj:3e43
PDBsum3e43
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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