Structure of PDB 3e3g Chain B

Receptor sequence
>3e3gB (length=207) Species: 727 (Haemophilus influenzae) [Search protein sequence]
MDKIKQLFANNYSWAQRMQTPHYLWIACSDSRVPAEKLTNLEPGELFVHR
NVANQVIHTDFNCLSVVQYAVDVLKIEHIIICGHTNCGGIHAAMADKDLG
LINNWLLHIRDIWFKHGHLLGKLSPEKRADMLTKINVAEQVYNLGRTSIV
KSAWERGQKLSLHGWVYDVNDGFLVDQGVMATSRETLEISYRNAIARLSI
LDEENIL
3D structure
PDB3e3g Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase .
ChainB
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C42 D44 R46 H98 C101
Catalytic site (residue number reindexed from 1) C28 D30 R32 H84 C87
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 B R160 R198 R146 R184
BS02 ZN B C42 D44 H98 C101 C28 D30 H84 C87
BS03 SO4 B P48 R64 P34 R50
BS04 SO4 B S45 R46 H98 Y181 V183 S31 R32 H84 Y167 V169
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e3g, PDBe:3e3g, PDBj:3e3g
PDBsum3e3g
PubMed20359198
UniProtP45148|CAN_HAEIN Carbonic anhydrase 2 (Gene Name=can)

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