Structure of PDB 3e0d Chain B

Receptor sequence
>3e0dB (length=1148) Species: 271 (Thermus aquaticus) [Search protein sequence]
LKFAHLHQHTQFSLLNGAAKLQDLLKWVKETTPEDPALAMTDHGNLFGAV
EFYKKATAMGVKPIIGYEAYVAAESRFDRKRGGYFHLTLLAKDFTGYQNL
VRLASRAYLEGFYEKPRIDREILREHAQGLIALSGCLGAEIPQFILQDRL
DLAEARLNEDLSIFGDRFFIEIQNHGLPEQKKVNQVLKEFARKYGLGMVA
TNNGHYVRKEDARAHEVLLAIQSKTTLDDPERWRFPCDEFYVKTPEEMRA
MLPEAEWGDEPFDNTVEIARMCDVDLPIGDKMVYRIPRFPLGRTEAQYLR
ELTFLGLLRRYPDRITEAFYREVLRLLDERALAEALARVEEKAWEELRKR
EWTAEAILHRALYELSVIERMGFPGYFLIVQDYINWARGHGVSVGPGRGS
AAGSLVAYAVGITNIDPLRFGLLFERFLNPERVSMPDIDTDFSDRERDRV
IQYVRERYGEDKVAQIGTFGSLASKAALKDVARVYGIPHKKAEELAKLIP
VQFGKPKPLQEAFEAEPELRAEMEKDERIRQVIEVAMRLEGLNRHASVHA
AGVVIAAEPLTDLVPLMRDQEGRPVTQYDMGAVEALGLLKMDFLGLRTLT
FLDEARRIVKESKGVELDYDRLPLDDPKTFELLSRGETKGVFQLESGGMT
ATVRGLKPRRLEDIIALVSLYRPGPMEHIPTYIRRHHGQEPVSYAEFPHA
EKYLRPILDETYGIPVYQEQIMQIASQVAGYSLGEADLLRRAMGKKRVEE
MQKHRERFVRGAKERGVPEEEANRLFDMLEAFANYGFNKSHAAAYSLLSY
QTAYVKAHYPVEFMAALLSVERHDSDKVAEYIRDARALGIPVLPPDVNRS
GFDFKVVGEEILFGLSAVKNVGEMAARAILEERERGGPFKSLGDFLKRLP
EQVVNKRALESLVKAGALDAFGDRARLLASLEPLLRWAAETRERGRSGLV
GLFAEVEEPPLVEASPLDEITMLRYEKEALGIYVSGHPVLRYPGLREVAS
CTIEELSEFVRELPGKPKVLLSGMVEEVRFTLSDETGALEVVKEDIPLLV
LAEVERVLAQAVWTLEEVLEAPKALEVEVDHALLDEKGARLKSLLDEHPG
SLPVYLRVLGPFGEALFALREVRVGEEALGLLEAEGYRAYLVPDREVF
3D structure
PDB3e0d Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit.
ChainB
Resolution4.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K233 D470 R473 R509 S573 A576 G621 L622 R623 S672 E927 R933 K224 D444 R447 R483 S547 A550 G595 L596 R597 S646 E901 R907
BS02 dna B R424 D465 K531 M606 K616 D618 R398 D439 K505 M580 K590 D592
BS03 CA B D463 D465 D437 D439
BS04 DTP B R424 G425 S426 D465 H817 R398 G399 S400 D439 H791
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e0d, PDBe:3e0d, PDBj:3e0d
PDBsum3e0d
PubMed18691598
UniProtQ9XDH5|DPO3A_THEAQ DNA polymerase III subunit alpha (Gene Name=dnaE)

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