Structure of PDB 3dzv Chain B

Receptor sequence
>3dzvB (length=265) Species: 1351 (Enterococcus faecalis) [Search protein sequence]
MKTSVKFETIFPLTTAPLIQCITNEITCESMANALLYIDAKPIMADDPRE
FPQMFQQTSALVLNLGHLSQEREQSLLAASDYARQVNKLTVVDLVGYGAS
DIRNEVGEKLVHNQPTVVKGNLSEMRTFCQLVSHPLDQSEEAIEELIQAL
RQQTQKFPQTVFLATGIQDVLVSQEQVIVLQNGVPELDCFTGTGDLVGAL
VAALLGEGNAPMTAAVAAVSYFNLCGEKAKTKSQGLADFRQNTLNQLSLL
MKEKDWFEAVKGRVL
3D structure
PDB3dzv Crystal structure of 4-methyl-5-(beta-hydroxyethyl)thiazole kinase (NP_816404.1) from ENTEROCOCCUS FAECALIS V583 at 2.57 A resolution
ChainB
Resolution2.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.50: hydroxyethylthiazole kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B T172 G173 D176 N189 V191 P192 L194 D195 T200 G201 N230 T165 G166 D169 N182 V184 P185 L187 D188 T193 G194 N223
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004417 hydroxyethylthiazole kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0009228 thiamine biosynthetic process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3dzv, PDBe:3dzv, PDBj:3dzv
PDBsum3dzv
PubMed
UniProtQ830K4|THIM_ENTFA Hydroxyethylthiazole kinase (Gene Name=thiM)

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