Structure of PDB 3dws Chain B

Receptor sequence
>3dwsB (length=304) Species: 5664 (Leishmania major) [Search protein sequence]
HHHMSLAVEAVKDFLLKLQDDICEALEAEDGQATFVEDKWTREGGGGGRT
RVMVDGAVIEKGGVNFSHVYGKGLPMSSTERHPDIAGCNFEAMGVSLVIH
PKNPHVPTSHANVRLFVAEREGKEPVWWFGGGFDLTPYYAVEEDCRDFHQ
VAQDLCKPFGADVYARFKGWCDEYFFIPYRNEARGIGGLFFDDLNEWPFE
KCFEFVQAVGKGYMDAYIPIVNRRKNTPYTEQQVEFQEFRRGRYAEFNLV
IDRGTKFGLQSGGRTESILISLPPRARWGYNWQPEPGTPEARLTEYFLTK
RQWV
3D structure
PDB3dws Leishmania major Coproporphyrinogen III Oxidase with bound ligand
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.3.3: coproporphyrinogen oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FIC B S93 H107 N109 R111 G251 S96 H110 N112 R114 G254
Gene Ontology
Molecular Function
GO:0004109 coproporphyrinogen oxidase activity
GO:0016491 oxidoreductase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006783 heme biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3dws, PDBe:3dws, PDBj:3dws
PDBsum3dws
PubMed
UniProtP84155|HEM6_LEIMA Oxygen-dependent coproporphyrinogen-III oxidase (Gene Name=LMAJ006828)

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