Structure of PDB 3ds3 Chain B

Receptor sequence
>3ds3B (length=73) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence]
TSILDIRQGPKEPFRDYVDRFAKTLRAEQASQEVKNWMTETLLVQNANPD
CKTILKALGPGATLEEMMTACQG
3D structure
PDB3ds3 Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B D166 F168 A169 L172 R173 Q179 K182 N183 T186 L211 M214 M215 D19 F21 A22 L25 R26 Q32 K35 N36 T39 L64 M67 M68
External links
PDB RCSB:3ds3, PDBe:3ds3, PDBj:3ds3
PDBsum3ds3
PubMed18772135
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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