Structure of PDB 3drt Chain B

Receptor sequence

>3drtB (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]

RITLKESGPPLVKPTQTLTLTCSFSGFSLSDFGVGVGWIRQPPGKALEWL
AIIYSDDDKRYSPSLNTRLTITKDTSKNQVVLVMTRVSPVDTATYFCAHR
RGPTGPVNAMDVWGQGITVTISSTSTKGPSVFPLAPGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYTCN
VNHKPSNTKVDKRVEP

3D structure

PDB

3drt Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5.

Chain

Resolution

3.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	G33 Y52 D56 R58 R95 P98 V100K	G33 Y54 D58 R60 R100 P103 V107

External links

PDB	RCSB:3drt, PDBe:3drt, PDBj:3drt
PDBsum	3drt
PubMed	19754136

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