Structure of PDB 3dr4 Chain B

Receptor sequence
>3dr4B (length=366) Species: 155892 (Caulobacter vibrioides) [Search protein sequence]
RISVAAPRLDGNERDYVLECMDTTWISSVGRFIVEFEKAFADYCGVKHAI
ACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYCGATPVLVDN
DPRTFNLDAAKLEALITPRTKAIMPVHLYGQICDMDPILEVARRHNLLVI
EDAAEAVGATYRGKKSGSLGDCATFSFFGNAIITTGEGGMITTNDDDLAA
KMRLLRGQGMDPNRRYWFPIVGFNYRMTNIQAAIGLAQLERVDEHLAARE
RVVGWYEQKLARLGNRVTKPHVALTGRHVFWMYTVRLGEGLSTTRDQVIK
DLDALGIESRPVFHPMHIMPPYAHLATDDLKIAEACGVDGLNLPTHAGLT
EADIDRVIAALDQVLV
3D structure
PDB3dr4 Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
ChainB
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y86 D157 E160 F183 A186 Y221 R231
Catalytic site (residue number reindexed from 1) Y81 D152 E155 F178 A181 Y216 R226
Enzyme Commision number 2.6.1.102: GDP-perosamine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G4M B T29 W30 S32 R220 Y221 N229 T24 W25 S27 R215 Y216 N224
BS02 G4M B A10 P12 N59 G60 T61 Y86 D157 A159 E160 S181 F183 G184 N185 E313 R315 F318 A5 P7 N54 G55 T56 Y81 D152 A154 E155 S176 F178 G179 N180 E308 R310 F313
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0102933 GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3dr4, PDBe:3dr4, PDBj:3dr4
PDBsum3dr4
PubMed18795799
UniProtQ9A9H3|GDPPS_CAUVC GDP-perosamine synthase (Gene Name=per)

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