Structure of PDB 3do7 Chain B

Receptor sequence
>3do7B (length=293) Species: 9606 (Homo sapiens) [Search protein sequence]
GPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYE
GPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL
GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMD
LSIVRLRFSAFLRDSDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKT
AGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYA
IVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLV
3D structure
PDB3do7 NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
ChainB
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R52 R54 S61 H62 R16 R18 S25 H26
BS02 dna B R52 Y55 C57 T142 K143 P223 Q254 R16 Y19 C21 T106 K107 P187 Q218
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3do7, PDBe:3do7, PDBj:3do7
PDBsum3do7
PubMed
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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