Structure of PDB 3di1 Chain B

Receptor sequence
>3di1B (length=291) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence]
MTHLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAES
PTLTTDEKERILKTVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGAD
AIMLITPYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETV
EILSQHPYIVALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQR
GGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTLLSALSVDINP
IPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKA
3D structure
PDB3di1 Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T46 Y109 Y135 R140 K163 I206
Catalytic site (residue number reindexed from 1) T46 Y109 Y135 R140 K163 I206
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PYR B A11 G45 T46 T47 Y135 K163 A11 G45 T46 T47 Y135 K163
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:3di1, PDBe:3di1, PDBj:3di1
PDBsum3di1
PubMed18671976
UniProtQ5HG25|DAPA_STAAC 4-hydroxy-tetrahydrodipicolinate synthase (Gene Name=dapA)

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