Structure of PDB 3dh7 Chain B

Receptor sequence
>3dh7B (length=318) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
KHLEACLEGEVAYQKTTTGLEGFRLRYQALAGLALSEVDLTTPFLGKTLK
APFLIGAMTERINLALAEAAEALGVGMMLGSGRILLERPEALRSFRVRKV
APKALLIANLGLAQLRRYGRDDLLRLVEMLEADALAFHVNPLQEAVQRGD
TDFRGLVERLAELLPLPFPVMVKEVGHGLSREAALALRDLPLAAVDVAGA
GGTSWARVEEWVRFGEVRHPELCEIGIPTARAILEVREVLPHLPLVASGG
VYTGTDGAKALALGADLLAVARPLLRPALEGAERVAAWIGDYLEELRTAL
FAIGARNPKEARGRVERV
3D structure
PDB3dh7 Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate
ChainB
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.3.2: isopentenyl-diphosphate Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN B C14 A65 M66 T67 N123 H152 K187 V189 T217 W219 G264 Y266 A285 R286 C6 A57 M58 T59 N109 H138 K173 V175 T203 W205 G250 Y252 A271 R272
BS02 POP B S95 R97 L124 Q128 H152 S81 R83 L110 Q114 H138
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004452 isopentenyl-diphosphate delta-isomerase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3dh7, PDBe:3dh7, PDBj:3dh7
PDBsum3dh7
PubMed18693754
UniProtQ53W52

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