Structure of PDB 3dfc Chain B

Receptor sequence
>3dfcB (length=280) Species: 9606 (Homo sapiens) [Search protein sequence]
TVFRQENVDDYYDTGEELGSGKFAVVKKCREKSTGLQYAAKFIKKRRTKS
SRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGEL
FDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRN
VPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMW
SIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDF
IRRLLVKDPKKRMTIQDSLQHPWIKPPQFE
3D structure
PDB3dfc High resolution crystal structures of the death associated protein kinase catalytic domain with a key point mutation in the glycine-rich loop
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N144 D161
Catalytic site (residue number reindexed from 1) N143 D160
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B G20 S21 G22 K23 F24 V27 A40 K42 V96 E100 M146 I160 D161 G19 S20 G21 K22 F23 V26 A39 K41 V95 E99 M145 I159 D160
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3dfc, PDBe:3dfc, PDBj:3dfc
PDBsum3dfc
PubMed
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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