Structure of PDB 3df0 Chain B

Receptor sequence
>3df0B (length=174) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTC
RSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNEL
PGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFR
SLDKNGTGQIQVNIQEWLQLTMYS
3D structure
PDB3df0 Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
ChainB
Resolution2.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F166 G189 I191
Catalytic site (residue number reindexed from 1) F70 G93 I95
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B A111 D114 E116 E121 A15 D18 E20 E25
BS02 CA B E116 D154 D156 T158 K160 L161 E165 E20 D58 D60 T62 K64 L65 E69
BS03 CA B D184 D186 S188 T190 E195 D88 D90 S92 T94 E99
BS04 CA B D139 D227 D229 N230 D43 D131 D133 N134
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:3df0, PDBe:3df0, PDBj:3df0
PDBsum3df0
PubMed19020622
UniProtQ64537|CPNS1_RAT Calpain small subunit 1 (Gene Name=Capns1)

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