Structure of PDB 3d9t Chain B

Receptor sequence
>3d9tB (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
GSSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCF
CCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRY
3D structure
PDB3d9t The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B D297 K299 G306 L307 R308 W310 D314 E319 W323 D46 K48 G55 L56 R57 W59 D63 E68 W72
BS02 ZN B C300 C303 H320 C327 C49 C52 H69 C76
External links
PDB RCSB:3d9t, PDBe:3d9t, PDBj:3d9t
PDBsum3d9t
PubMed19153467
UniProtQ13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)

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