Structure of PDB 3d6t Chain B

Receptor sequence
>3d6tB (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
MKLMIVGNTGSGKTTLLQLMGIDVKDWPLVLVWDFAGREEFYSTHPHFMT
QRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDKI
LLGFPAIRDYHFVNATEESLRKTII
3D structure
PDB3d6t Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
ChainB
Resolution2.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B H1453 D1455 N1489 A1490 H93 D95 N114 A115
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3d6t, PDBe:3d6t, PDBj:3d6t
PDBsum3d6t
PubMed18230735
UniProtQ5S007|LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 (Gene Name=LRRK2)

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