Structure of PDB 3cke Chain B

Receptor sequence
>3ckeB (length=297) Species: 33178 (Aspergillus terreus) [Search protein sequence]
SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSR
VTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPIS
RGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTR
ARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCS
KHLSVVNDIYSYEKELYTSILCTSVQILAQEADVTAEAAKRVLFVMCREW
ELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV
3D structure
PDB3cke X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis.
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y67 F87 F153 K181 W308
Catalytic site (residue number reindexed from 1) Y55 F75 F141 K169 W288
Enzyme Commision number 4.2.3.9: aristolochene synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FDF B F87 D90 F153 R314 F75 D78 F141 R294
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0045483 aristolochene synthase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3cke, PDBe:3cke, PDBj:3cke
PDBsum3cke
PubMed18385128
UniProtQ9UR08|ARIS_ASPTE Aristolochene synthase (Gene Name=Ari1)

[Back to BioLiP]