Structure of PDB 3cep Chain B

Receptor sequence
>3cepB (length=393) [Search protein sequence]
TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKN
YAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRM
GKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRL
MGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIV
REFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVG
LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSIS
AGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALES
SHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKAR
3D structure
PDB3cep Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.20: tryptophan synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B H86 K87 T190 G232 G233 G234 S235 N236 G303 E350 S377 G378 H85 K86 T189 G231 G232 G233 S234 N235 G302 E349 S376 G377
BS02 MH6 B K87 T110 G111 A112 G113 Q114 H115 K86 T109 G110 A111 G112 Q113 H114
BS03 IDM B K87 L166 T190 G233 F306 K86 L165 T189 G232 F305
Gene Ontology
Molecular Function
GO:0004834 tryptophan synthase activity
GO:0005515 protein binding
GO:0016829 lyase activity
GO:0042802 identical protein binding
Biological Process
GO:0000162 tryptophan biosynthetic process
GO:0006568 tryptophan metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3cep, PDBe:3cep, PDBj:3cep
PDBsum3cep
PubMed18351684
UniProtP0A2K1|TRPB_SALTY Tryptophan synthase beta chain (Gene Name=trpB)

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