Structure of PDB 3c8e Chain B

Receptor sequence
>3c8eB (length=283) Species: 562 (Escherichia coli) [Search protein sequence]
YQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGTPNG
QKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPALR
DHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAP
FLGGGFGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEY
TIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRG
RIVNRTNGPLNEQLHERHDASDFETNTEDKRQG
3D structure
PDB3c8e Structure and Function of YghU, a Nu-Class Glutathione Transferase Related to YfcG from Escherichia coli.
ChainB
Resolution1.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.1.-
1.8.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH B T52 N54 Q87 K100 I101 E117 S118 T47 N49 Q82 K95 I96 E112 S113 MOAD: Kd=0.07mM
PDBbind-CN: -logKd/Ki=4.15,Kd=0.07mM
BS02 GSH B F22 N26 T52 N54 P155 G158 W215 F17 N21 T47 N49 P150 G153 W210 MOAD: Kd=0.07mM
PDBbind-CN: -logKd/Ki=4.15,Kd=0.07mM
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0015036 disulfide oxidoreductase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0098869 cellular oxidant detoxification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3c8e, PDBe:3c8e, PDBj:3c8e
PDBsum3c8e
PubMed21222452
UniProtQ46845|YGHU_ECOLI Disulfide-bond oxidoreductase YghU (Gene Name=yghU)

[Back to BioLiP]