Structure of PDB 3c79 Chain B

Receptor sequence
>3c79B (length=212) Species: 6500 (Aplysia californica) [Search protein sequence]
DDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSS
TNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSST
RPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGS
WVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYI
DVNLVVKFRERR
3D structure
PDB3c79 Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore.
ChainB
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IM4 B Y93 W147 V148 Y188 C190 Y195 Y97 W151 V152 Y192 C194 Y199 MOAD: Kd=63nM
BindingDB: Ki=19nM
BS02 IM4 B Y55 M116 I118 Y59 M120 I122 MOAD: Kd=63nM
BindingDB: Ki=19nM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:3c79, PDBe:3c79, PDBj:3c79
PDBsum3c79
PubMed18477694
UniProtQ8WSF8

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