Structure of PDB 3c6p Chain B

Receptor sequence
>3c6pB (length=567) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
PEEVLEHVFSFIQLDKDRNSVSLVCKSWYEIERWCRRKVFIGNCYAVSPA
TVIRRFPKVRSVELKGKPHFADFNLVPDGWGGYVYPWIEAMSSSYTWLEE
IRLKRMVVTDDCLELIAKSFKNFKVLVLSSCEGFSTDGLAAIAATCRNLK
ELDLRESDVDDVSGHWLSHFPDTYTSLVSLNISCLASEVSFSALERLVTR
CPNLKSLKLNRAVPLEKLATLLQRAPQLEELGTGGYTAEVRPDVYSGLSV
ALSGCKELRCLSGFWDAVPAYLPAVYSVCSRLTTLNLSYATVQSYDLVKL
LCQCPKLQRLWVLDYIEDAGLEVLASTCKDLRELRVFPSEPFVMEPNVAL
TEQGLVSVSMGCPKLESVLYFCRQMTNAALITIARNRPNMTRFRLCIIEP
KAPDYLTLEPLDIGFGAIVEHCKDLRRLSLSGLLTDKVFEYIGTYAKKME
MLSVAFAGDSDLGMHHVLSGCDSLRKLEIRDCPFGDKALLANASKLETMR
SLWMSSCSVSFGACKLLGQKMPKLNVEVIDERGAPDSRPESCPVERVFIY
RTVAGPRFDMPGFVWNM
3D structure
PDB3c6p Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IHP B K74 K113 R114 R344 R401 R436 R484 K485 K65 K104 R105 R335 R392 R427 R475 K476
BS02 2S3 B F380 R403 L404 S438 S462 R489 F371 R394 L395 S429 S453 R480
Gene Ontology
Molecular Function
GO:0000822 inositol hexakisphosphate binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0010011 auxin binding
GO:0038198 auxin receptor activity
Biological Process
GO:0006952 defense response
GO:0009733 response to auxin
GO:0009734 auxin-activated signaling pathway
GO:0009873 ethylene-activated signaling pathway
GO:0010152 pollen maturation
GO:0010311 lateral root formation
GO:0016036 cellular response to phosphate starvation
GO:0016567 protein ubiquitination
GO:0048443 stamen development
Cellular Component
GO:0005634 nucleus
GO:0019005 SCF ubiquitin ligase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3c6p, PDBe:3c6p, PDBj:3c6p
PDBsum3c6p
PubMed18391211
UniProtQ570C0|TIR1_ARATH Protein TRANSPORT INHIBITOR RESPONSE 1 (Gene Name=TIR1)

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