Structure of PDB 3c5j Chain B

Receptor sequence
>3c5jB (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
RPRFLELLKSECHFFNGTERVRFLERYFHNQEEFVRFDSDVGEYRAVTEL
GRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTVQRRVHPQVTVYP
AKHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTL
VMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB3c5j The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B L11 S13 F26 E28 Y30 W61 K71 Y78 H81 N82 V85 L8 S10 F23 E25 Y27 W58 K68 Y75 H78 N79 V82
Gene Ontology
Biological Process
GO:0002250 adaptive immune response
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3c5j, PDBe:3c5j, PDBj:3c5j
PDBsum3c5j
PubMed18697946
UniProtB8YAC7

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