Structure of PDB 3c25 Chain B

Receptor sequence

>3c25B (length=353) Species: 1823 (Nocardia otitidiscaviarum) [Search protein sequence]

ANFIAEFFGHRVYPEVVSTEAARNDQATGTCPFLTAAKLVETSCVKAETS
RGVCVVNTAVDNERYDWLVCPNRALDPLFMSAASRKLFGYGPTEPLQFIA
APTLADQAVRDGIREWLDRGVHVVAYFQEKLGGELSISKTDSSPEFSFDW
TLAEVESIYPVPKIKRYGVLEIQTMDFHGSYKHAVGAIDIALVEGIDFHG
WLPTPAGRAALSKKMEGPNLSNVFKRTFYQMAYKFALSGHQRCAGTGFAI
PQSVWKSWLRHLANPTLIDNGDGTFSLGDTRNDSENAWIFVFELDPDTDA
SPRPLAPHLEIRVNVDTLIDLALRESPRAALGPSGPVATFTDKVEARMLR
FWP

3D structure

PDB

3c25 Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.

Chain

Resolution

2.5 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	K57 T60 S61 V80 E156 F157 S158 D160 T185 M186 D187 F188 H189 G190 S191 Y192 R237 Q241 K245 R358	K46 T49 S50 V69 E145 F146 S147 D149 T174 M175 D176 F177 H178 G179 S180 Y181 R226 Q230 K234 R347
BS02	dna	B	N13 V71 K141 G144 E145 H189 N230 S232 K236	N2 V60 K130 G133 E134 H178 N219 S221 K225
BS03	FE	B	C55 C65 C81	C44 C54 C70
BS04	CA	B	E145 D160	E134 D149
BS05	CA	B	E182 I183	E171 I172

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:3c25, PDBe:3c25, PDBj:3c25
PDBsum	3c25
PubMed	18400177
UniProt	Q2I6W2

[Back to BioLiP]