Structure of PDB 3c23 Chain B

Receptor sequence
>3c23B (length=349) Species: 2336 (Thermotoga maritima) [Search protein sequence]
VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGG
FWLDTDFSAEKLYELSKMDGAIVLSEDITKIYYANVHLVPDPTIPTGETG
TRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQ
AISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEI
RPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNIL
QDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLS
IGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT
3D structure
PDB3c23 Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.85: diadenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AT B G76 L94 T107 R108 T111 S127 R128 R130 G70 L88 T101 R102 T105 S121 R122 R124
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004016 adenylate cyclase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0106408 diadenylate cyclase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3c23, PDBe:3c23, PDBj:3c23
PDBsum3c23
PubMed18439896
UniProtQ9WY43|DISA_THEMA DNA integrity scanning protein DisA (Gene Name=disA)

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