Structure of PDB 3bqm Chain B

Receptor sequence
>3bqmB (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSY
KTEFDFSDYVKWKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR
PDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKF
ASKPASEFVKILDTFEKLKDLFTELQKKIYVI
3D structure
PDB3bqm Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BQM B F153 Y166 I235 Y257 E284 F285 K287 L302 F26 Y39 I108 Y130 E157 F158 K160 L175 MOAD: Ki=2nM
BindingDB: IC50=1.7nM
External links
PDB RCSB:3bqm, PDBe:3bqm, PDBj:3bqm
PDBsum3bqm
PubMed18778938
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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