Structure of PDB 3bje Chain B

Receptor sequence
>3bjeB (length=327) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
DLPIGKDGTTLHLKCKSDELADRIIFVGDPGRVDVISGYFDKDSIRASRD
HREIRFATGTYKGTPVTVISTGMGVDNIEIVLNEIHALKEYDMERGQWRH
RKGDADAPSAGPFFDPSTMKIIRLGTCGSPAESVPPLALAVTRHAIGMDN
TSLYYSAGTRETSKDQQEIRRIVREQTGLRAIDIYTSMAHPNITKSICAA
CDAHNAATGSEADKQQYVIGTTATASGFYGCQGRRVGRFMKHLTVPNMVE
ELGSLKFNLSNGVEVVTNIEMETSAICYLSDMLGYQAGAACVVVSKRVGE
KKMFLGDQLDAAMKRCIKIILEALVSA
3D structure
PDB3bje The Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine Phosphorylase
ChainB
Resolution1.44 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R1P B H26 R66 H12 R52
BS02 R1P B G42 R46 R137 T140 M285 E286 G28 R32 R123 T126 M271 E272
BS03 URA B C141 G142 F242 Q246 R248 V308 S309 C127 G128 F228 Q232 R234 V294 S295
BS04 CA B M87 D90 N91 M73 D76 N77
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
GO:0004850 uridine phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006218 uridine catabolic process
GO:0009116 nucleoside metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0097014 ciliary plasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3bje, PDBe:3bje, PDBj:3bje
PDBsum3bje
PubMed20070944
UniProtQ57VZ2

[Back to BioLiP]