Structure of PDB 3bj7 Chain B

Receptor sequence
>3bj7B (length=161) Species: 10090 (Mus musculus) [Search protein sequence]
KFKIRPATASDCSDILRLIKELAKYEYMEDQVILTEKDLQEDGFGEHPFY
HCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRG
FGIGSEILKNLSQVAMKCRCSSMHFLVAEWNEPSINFYKRRGASDLGWRL
FKIDKEYLLKM
3D structure
PDB3bj7 The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.57: diamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B F94 F95 V96 R101 G102 F103 G104 G106 S107 N133 S136 F139 Y140 R142 R143 F92 F93 V94 R99 G100 F101 G102 G104 S105 N131 S134 F137 Y138 R140 R141
Gene Ontology
Molecular Function
GO:0004145 diamine N-acetyltransferase activity
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0009447 putrescine catabolic process
GO:0032918 spermidine acetylation
GO:0042127 regulation of cell population proliferation
GO:0046208 spermine catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:3bj7, PDBe:3bj7, PDBj:3bj7
PDBsum3bj7
PubMed18690703
UniProtP48026|SAT1_MOUSE Diamine acetyltransferase 1 (Gene Name=Sat1)

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