Structure of PDB 3bi5 Chain B

Receptor sequence
>3bi5B (length=499) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGR
KYDIGASWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDEERGRV
DHDKELLLEIVDNEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLT
NDQIRYLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQR
IAQSFPQNWLKLSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSV
LNLSVQPEKNLRGRIEFQPPLKPVIQDAFDKIHFGALGKVIFEFEECCWS
NESSKIVTLANSTNEFVEIVRNAENLDELDSMLERETSVTCWSQPLFFVN
LSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMKCLDSE
DVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPGDDPVDM
VVAMSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREATRISDLLKLEH
3D structure
PDB3bi5 Crystal structures of fms1 in complex with its inhibitors
ChainB
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H67
Catalytic site (residue number reindexed from 1) H60
Enzyme Commision number 1.5.3.17: non-specific polyamine oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G15 A19 E39 A40 R41 G46 R47 G62 A63 S64 W65 H67 V223 V253 G270 W440 E479 G487 C488 A489 G8 A12 E32 A33 R34 G39 R40 G55 A56 S57 W58 H60 V216 V246 G263 W428 E467 G475 C476 A477
BS02 DIA B H67 L173 W174 F359 Y450 G487 H60 L166 W167 F347 Y438 G475
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0016491 oxidoreductase activity
GO:0046592 polyamine oxidase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0052897 N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity
GO:0052901 spermine oxidase activity
GO:0052903 N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity
Biological Process
GO:0006338 chromatin remodeling
GO:0015940 pantothenate biosynthetic process
GO:0046208 spermine catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3bi5, PDBe:3bi5, PDBj:3bi5
PDBsum3bi5
PubMed
UniProtP50264|FMS1_YEAST Polyamine oxidase FMS1 (Gene Name=FMS1)

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