Structure of PDB 3bbd Chain B

Receptor sequence
>3bbdB (length=204) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEM
RGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYF
RFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPK
LLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICY
SLSF
3D structure
PDB3bbd The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
ChainB
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B M141 T142 K143 I161 G162 F164 P165 G167 I185 K188 L190 V195 M140 T141 K142 I160 G161 F163 P164 G166 I184 K187 L189 V194
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0019843 rRNA binding
GO:0042803 protein homodimerization activity
GO:0070037 rRNA (pseudouridine) methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0042254 ribosome biogenesis
GO:0070475 rRNA base methylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3bbd, PDBe:3bbd, PDBj:3bbd
PDBsum3bbd
PubMed18208838
UniProtQ57977|NEP1_METJA Ribosomal RNA small subunit methyltransferase Nep1 (Gene Name=nep1)

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