Structure of PDB 3ay0 Chain B

Receptor sequence
>3ay0B (length=314) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
PLCLKINKKHGEQTRRILIENNLLNKDYKITSEGNYLYLPIKDVDEDILK
SILNIEFELVDKEIISKKYRKEIDEGLISLSYDVVGDLVILQISDEVDEK
IRKEIGELAYKLIPCKGVFRRKRVRELEHLAGENRTLTIHKENGYRLWVD
IAKVYFSPRLGGERARIMKKVSLNDVVVDMFAGVGPFSIACKNAKKIYAI
DINPHAIELLKKNIKLNKLEHKIIPILSDVREVDVKGNRVIMNLPKFAHK
FIDKALDIVEEGGVIHYYTIGKDFDKAIKLFEKKCDCEVLEKRIVKSYAP
REYILALDFKINKK
3D structure
PDB3ay0 Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
ChainB
Resolution3.05 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H227 E230 H205 E208
BS02 ADN B Y177 F203 D223 I224 D251 V252 L266 Y155 F181 D201 I202 D229 V230 L244
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008175 tRNA methyltransferase activity
GO:0016740 transferase activity
GO:0052906 tRNA (guanine(37)-N1)-methyltransferase activity
Biological Process
GO:0002939 tRNA N1-guanine methylation
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ay0, PDBe:3ay0, PDBj:3ay0
PDBsum3ay0
PubMed21602303
UniProtQ58293|TRM5B_METJA tRNA (guanine(37)-N1)-methyltransferase Trm5b (Gene Name=trm5b)

[Back to BioLiP]