Structure of PDB 3aut Chain B

Receptor sequence
>3autB (length=262) Species: 1404 (Priestia megaterium) [Search protein sequence]
HMYTDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAK
KEVEEAGGQAIIVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPV
PSHELSLDNWNKVIDTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEM
IPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAMNTPINAEK
FADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFADGG
MTKYPSFQAGRG
3D structure
PDB3aut Structure-guided mutagenesis for the improvement of substrate specificity of Bacillus megaterium glucose 1-dehydrogenase IV
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G18 S145 Y158 K162
Catalytic site (residue number reindexed from 1) G19 S146 Y159 K163
Enzyme Commision number 1.1.1.47: glucose 1-dehydrogenase [NAD(P)(+)].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI B T17 G18 L19 D65 V66 N92 A93 G94 V95 M143 S144 S145 Y158 P188 G189 M191 T193 I195 N196 T18 G19 L20 D66 V67 N93 A94 G95 V96 M144 S145 S146 Y159 P189 G190 M192 T194 I196 N197
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0047934 glucose 1-dehydrogenase (NAD+) activity
GO:0047935 glucose 1-dehydrogenase (NADP+) activity
GO:0047936 glucose 1-dehydrogenase [NAD(P)+] activity

View graph for
Molecular Function
External links
PDB RCSB:3aut, PDBe:3aut, PDBj:3aut
PDBsum3aut
PubMed22804868
UniProtP39485|DHG4_PRIMG Glucose 1-dehydrogenase 4 (Gene Name=gdhIV)

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