Structure of PDB 3anx Chain B

Receptor sequence
>3anxB (length=313) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MDYGMYFFEHVTPYETLVRRMERVIASGKTPFQDYFLFESKGFGKVLILD
KDVQSTERDEYIYHETLVHPAMLTHPEPKRVLIVGGGEGATLREVLKHPT
VEKAVMVDIDGELVEVAKRHMPEWHQGAFDDPRAVLVIDDARAYLERTEE
RYDVVIIDLTDPVGEDNPARLLYTVEFYRLVKAHLNPGGVMGMQAGMILL
THHRVHPVVHRTVREAFRYVRSYKNHIPGFFLNFGFLLASDAFDPAAFSE
GVIEARIRERNLALRHLTAPYLEAMFVLPKDLLEALEKETMVSTDQNPFY
VTPEGEARQAPYK
3D structure
PDB3anx Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.104: N(1)-aminopropylagmatine synthase.
2.5.1.126: norspermine synthase.
2.5.1.22: spermine synthase.
2.5.1.79: thermospermine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MTA B Q33 Q54 G85 G86 G87 E88 D108 I109 L159 Q33 Q54 G85 G86 G87 E88 D108 I109 L159
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004766 spermidine synthase activity
GO:0010487 thermospermine synthase activity
GO:0016740 transferase activity
GO:0016768 spermine synthase activity
GO:0043918 cadaverine aminopropyltransferase activity
GO:0043919 agmatine aminopropyltransferase activity
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0008295 spermidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:3anx, PDBe:3anx, PDBj:3anx
PDBsum3anx
PubMed21458463
UniProtQ5SK28|SPEE_THET8 Polyamine aminopropyltransferase (Gene Name=speE)

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