Structure of PDB 3a8o Chain B

Receptor sequence
>3a8oB (length=212) Species: 1833 (Rhodococcus erythropolis) [Search protein sequence]
MDGVHDLAGVQGFGKVPHTVNADIGPTFHAEWEHLPYSLMFAGVAELGAF
SVDEVRYVVERMEPRHYMMTPYYERYVIGVATLMVEKGILTQDELESLAG
GPFPLSRPSESEGRPAPVETTTFEVGQRVRVRDEYVPGHIRMPAYCRGRV
GTISHRTTEKWPFPDAIGHGRNDAGEEPTYHVKFAAEELFGSDTDGGSVV
VDLFEGYLEPAA
3D structure
PDB3a8o Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase
ChainB
Resolution1.47 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R56 Y72 Y76
Catalytic site (residue number reindexed from 1) R56 Y72 Y76
Enzyme Commision number 4.2.1.84: nitrile hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TAY B Y37 Y72 Y76 Y37 Y72 Y76
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0018822 nitrile hydratase activity
GO:0046914 transition metal ion binding
GO:0080109 indole-3-acetonitrile nitrile hydratase activity

View graph for
Molecular Function
External links
PDB RCSB:3a8o, PDBe:3a8o, PDBj:3a8o
PDBsum3a8o
PubMed20221653
UniProtP13449|NHAB_RHOER Nitrile hydratase subunit beta (Gene Name=nthB)

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