Structure of PDB 3a3k Chain B

Receptor sequence
>3a3kB (length=429) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SDLTVAVVLPLTNTSYPWSWARVGPAVELALARVKARPDLLPGWTVRMVL
GSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHW
RVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQA
LVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLL
RAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKP
QKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFN
FTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQRMWNRS
FQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQELMAVSE
HKLYWPLGYPPPDVPKCGFDNEDPACNQD
3D structure
PDB3a3k Reversibly bound chloride in the atrial natriuretic peptide receptor hormone-binding domain: Possible allosteric regulation and a conserved structural motif for the chloride-binding site.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.2: guanylate cyclase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BR B P10 W18 S53 P84 C86 P10 W18 S53 P84 C86
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3a3k, PDBe:3a3k, PDBj:3a3k
PDBsum3a3k
PubMed20066666
UniProtP18910|ANPRA_RAT Atrial natriuretic peptide receptor 1 (Gene Name=Npr1)

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