Structure of PDB 2zpa Chain B

Receptor sequence
>2zpaB (length=662) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFEHTLKLRDALPGDWLWI
SPRPDALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWLVLLLPV
WEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNEAILWRQNQPF
SLAHFTPRTDWYPATGAPQPEQQQLLKQLMTMPPGVAAVTAARGRGKSAL
AGQLISRIAGRAIVTAPAKASTDVLAQFAGEKFRFIAPDALLASDEQADW
LVVDEAAAIPAPLLHQLVSRFPRTLLTTTVQGYEGTGRGFLLKFCARFPH
LHRFELQQPIRWAQGCPLEKMVSEALVFDDENFTHTPQGNIVISAFEQTL
WQSDPETPLKVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQAAGENEIAGA
LWLVDEGGLSQQLSQAVWAGFRRPRGNLVAQSLAAHGNNPLAATLRGRRV
SRIAVHPARQREGTGRQLIAGALQYTQDLDYLSVSFGYTGELWRFWQRCG
FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQW
NGETLPVDPLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELA
LPALRGRLQKNASDAQLCTTLKLSGRKMLLVRQREEAAQALFALNDVRTE
RLRDRITQWQLF
3D structure
PDB2zpa RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.193: tRNA(Met) cytidine acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO B I461 V463 R469 G471 G473 R474 V492 L500 F503 W504 R506 I453 V455 R461 G463 G465 R466 V484 L492 F495 W496 R498
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0051392 tRNA N-acetyltransferase activity
GO:0106226 peptide 2-hydroxyisobutyryltransferase activity
Biological Process
GO:0002101 tRNA wobble cytosine modification
GO:0008033 tRNA processing
GO:0051391 tRNA acetylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zpa, PDBe:2zpa, PDBj:2zpa
PDBsum2zpa
PubMed19322199
UniProtP76562|TMCA_ECOLI tRNA(Met) cytidine acetyltransferase TmcA (Gene Name=tmcA)

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