Structure of PDB 2zo1 Chain B

Receptor sequence
>2zo1B (length=206) Species: 10090 (Mus musculus) [Search protein sequence]
HMPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLV
LAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALN
CHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVV
KYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYL
EALANK
3D structure
PDB2zo1 The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
ChainB
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B H450 H455 R457 S458 N494 K495 R496 H34 H39 R41 S42 N78 K79 R80
BS02 dna B F437 R438 H450 V451 A452 G453 A468 G470 Y471 D474 Y483 T484 S486 R496 Y615 F21 R22 H34 V35 A36 G37 A52 G54 Y55 D58 Y67 T68 S70 R80 Y199
External links
PDB RCSB:2zo1, PDBe:2zo1, PDBj:2zo1
PDBsum2zo1
PubMed18772888
UniProtQ8VDF2|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)

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