Structure of PDB 2zne Chain B

Receptor sequence
>2zneB (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
QSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDR
ENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGY
RLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDG
WIQVSYEQYLSMVFSIV
3D structure
PDB2zne Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F85 G108 I110
Catalytic site (residue number reindexed from 1) F61 G84 I86
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B M71 Y91 W95 V98 Y102 R104 Q117 F122 Q159 R160 M47 Y67 W71 V74 Y78 R80 Q93 F98 Q135 R136
BS02 ZN B D36 D38 V42 E47 D12 D14 V18 E23
BS03 ZN B D103 D105 M109 E114 D79 D81 M85 E90
BS04 ZN B D171 D173 D147 D149
BS05 ZN B D105 D111 D81 D87
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2zne, PDBe:2zne, PDBj:2zne
PDBsum2zne
PubMed18940611
UniProtO75340|PDCD6_HUMAN Programmed cell death protein 6 (Gene Name=PDCD6)

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