Structure of PDB 2znb Chain B

Receptor sequence
>2znbB (length=226) Species: 817 (Bacteroides fragilis) [Search protein sequence]
QKSVKISDDISITQLSDKVYTYVSLAEIGMVPSNGMIVINNHQAALLDTP
INDAQTETLVNWVADSLHAKVTTFIPNHWHGDCIGGLGYLQKKGVQSYAN
QMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWL
PTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVP
GHGDYGGTELIEHTKQIVNQYIESTS
3D structure
PDB2znb Crystal structures of the cadmium- and mercury-substituted metallo-beta-lactamase from Bacteroides fragilis.
ChainB
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H99 H101 D103 H162 C181 K184 N193 H223
Catalytic site (residue number reindexed from 1) H78 H80 D82 H141 C160 K163 N172 H202
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CD B H99 H101 H162 H78 H80 H141
BS02 CD B D103 C181 H223 D82 C160 H202
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2znb, PDBe:2znb, PDBj:2znb
PDBsum2znb
PubMed9416622
UniProtP25910|BLAB_BACFG Metallo-beta-lactamase type 2 (Gene Name=ccrA)

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