Structure of PDB 2zgn Chain B

Receptor sequence
>2zgnB (length=158) [Search protein sequence]
QGVNIYNISAGTSVDLAAPVTTGDIVTFFSSALNLNAGAGNPNNTTLNLF
AENGAYLLHIAFRLQENVIIFNSRQPDGPWLVEQRVSDVANQFAGIDGKA
MVTVFDHGDKYQVVINEKTVIQYTKQISGLTSSLSYNATEETSIFSTVVE
AVTYTGLA
3D structure
PDB2zgn Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL B N43 H59 R63 W80 N43 H59 R63 W80
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0004536 DNA nuclease activity
GO:0030246 carbohydrate binding
GO:0030247 polysaccharide binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006915 apoptotic process
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2zgn, PDBe:2zgn, PDBj:2zgn
PDBsum2zgn
PubMed19361423
UniProtQ6WY08|ATLE_CYCAE Anti-tumor lectin (Fragment)

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