Structure of PDB 2zgm Chain B

Receptor sequence
>2zgmB (length=159) [Search protein sequence]
MQGVNIYNISAGTSVDLAAPVTTGDIVTFFSSALNLNAGAGNPNNTTLNL
FAENGAYLLHIAFRLQENVIIFNSRQPDGPWLVEQRVSDVANQFAGIDGK
AMVTVFDHGDKYQVVINEKTVIQYTKQISGLTSSLSYNATEETSIFSTVV
EAVTYTGLA
3D structure
PDB2zgm Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC B R63 E83 R85 R64 E84 R86
BS02 GAL B N43 H59 R63 N72 W80 E83 N44 H60 R64 N73 W81 E84
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0004536 DNA nuclease activity
GO:0030246 carbohydrate binding
GO:0030247 polysaccharide binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006915 apoptotic process
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zgm, PDBe:2zgm, PDBj:2zgm
PDBsum2zgm
PubMed19361423
UniProtQ6WY08|ATLE_CYCAE Anti-tumor lectin (Fragment)

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