Structure of PDB 2zej Chain B

Receptor sequence
>2zejB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
MKLMIVGNTGSGKTTLLQQLMKTQSATVGIDVKDWPILVLNVWDFAGREE
FYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILV
GTHLDVSDEKQRKACMSKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFK
3D structure
PDB2zej Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
ChainB
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B H1453 D1455 N1489 A1490 T1491 H103 D105 N139 A140 T141
BS02 GDP B G1344 G1346 K1347 T1348 T1349 G10 G12 K13 T14 T15
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:2zej, PDBe:2zej, PDBj:2zej
PDBsum2zej
PubMed18230735
UniProtQ5S007|LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 (Gene Name=LRRK2)

[Back to BioLiP]