Structure of PDB 2z6i Chain B

Receptor sequence
>2z6iB (length=321) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGGNAPKEV
VKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPS
KYMERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTT
MTLVRQVATAISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKES
NAHPNYKEKILKARDIDTTISAQHFGHAVRAIKNQLTRDFELAEKDAFKQ
EDPDLEIFEQMGAGALAKAVVHGDVDGGSVMAGQIAGLVSKEETAEEILK
DLYYGAAKKIQEEASRWTGVV
3D structure
PDB2z6i Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.13.12.16: nitronate monooxygenase.
1.3.-.-
1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B A158 I161 A158 I161
BS02 CA B E137 H144 E137 H144
BS03 FMN B G18 G19 M20 A21 N69 E137 A141 G142 G169 G170 G191 T192 M281 G18 G19 M20 A21 N69 E137 A141 G142 G169 G170 G191 T192 M281
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO:0016491 oxidoreductase activity
GO:0018580 nitronate monooxygenase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2z6i, PDBe:2z6i, PDBj:2z6i
PDBsum2z6i
PubMed18305197
UniProtQ9FBC5

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