Structure of PDB 2yxo Chain B

Receptor sequence
>2yxoB (length=265) Species: 274 (Thermus thermophilus) [Search protein sequence]
MVDSHVHTPLCGHAEGHPEAYLEEARAKGLKGVVFTDHSPMPPWYDPESR
MRLEALPFYLLALERVRERAQDLYVGIGLEADFHPGTEGFLAQLLRRYPF
DYVIGSVHYLGAWPLDHPDHQEEYAWRDLKEVFRAYFQEVEKAARSGLFH
AIGHLDLPKKFGHRLPEEALLELAEPALRAVAEAGLFLDVNTAGLRRPAK
EVYPAPALLRRARELGIGLVLGSDAHRPEEVGFAFPEVQALLAGLGFREA
YYFVEGSPVAYPLSR
3D structure
PDB2yxo Crystal Structure of Monofunctional Histidinol Phosphate Phosphatase from Thermus thermophilus HB8.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.15: histidinol-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 B H7 H38 H108 H226 H7 H38 H108 H226
BS02 ZN B E80 H108 H154 E80 H108 H154
BS03 FE B H13 H38 H226 H13 H38 H226
BS04 FE B H5 H7 E80 D224 H5 H7 E80 D224
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004401 histidinol-phosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2yxo, PDBe:2yxo, PDBj:2yxo
PDBsum2yxo
PubMed17929834
UniProtQ5SLG2

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