Structure of PDB 2ywv Chain B

Receptor sequence
>2ywvB (length=237) Species: 1462 (Geobacillus kaustophilus) [Search protein sequence]
MPTKQQLLYEGKAKKIYATDEPDVLWVEYKDSATAFNGEKKATIAGKGRL
NNEISSLLFLKLREAGIANHFIEKLSPTEQLVRRVTIIPLEVVVRNVVAG
SLAKRIGLEEGTPLEAPLVEFYYKNDDLGDPLLLEDHIFILKLASREEVA
ALKQAALAVNDVLRLHFAERNVRLIDFKLEFGRTADGAILLADEISPDTC
RLWDAKTNEKLDKDVFRRDLGSLTDAYEVILQRLGGE
3D structure
PDB2ywv Crystal structure of SAICAR synthetase from Geobacillus kaustophilus
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B Y9 G11 K12 A13 K14 L25 H70 V85 I87 K124 E180 D193 Y9 G11 K12 A13 K14 L25 H70 V85 I87 K124 E180 D193
Gene Ontology
Molecular Function
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
GO:0009236 cobalamin biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:2ywv, PDBe:2ywv, PDBj:2ywv
PDBsum2ywv
PubMed
UniProtQ5L3D5

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