Structure of PDB 2ypa Chain B

Receptor sequence
>2ypaB (length=73) Species: 9606 (Homo sapiens) [Search protein sequence]
EKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLI
LQQAVQVILGLEQQVRERNLNPK
3D structure
PDB2ypa Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B E555 R558 E17 R20
BS02 dna B N552 T584 K585 N14 T46 K47
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:2ypa, PDBe:2ypa, PDBj:2ypa
PDBsum2ypa
PubMed23831025
UniProtP15923|TFE2_HUMAN Transcription factor E2-alpha (Gene Name=TCF3)

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